EGFR-IN-7

Name: EGFR-IN-7
SKU: A18562
Price: 630 CNY
Rating: 5 (288 reviews)

目录号: A18562

EGFR 抑制剂

EGFR-IN-7（化合物34）是一种从专利WO2019015655A1中提取的选择性且高效的EGFR激酶抑制剂，对EGFR（WT）和EGFR（突变型C797S/T790M/L858R）的IC50分别为7.92 nM和0.218 nM，显示出抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥630.00	现货
5mg	¥1,645.00	现货
10mg	¥2,730.00	现货
25mg	¥4,690.00	现货
50mg	¥6,685.00	现货
100mg	¥8,925.00	现货
500mg	¥18,095.00	现货
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Data Sheet

SDS

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生物活性

Discription

EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18562
分子式	C32H41BrN9O2P
分子量	694.6
CAS号	2267329-76-8
SMILES	CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Insoluble
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.4 mL	71.98 mL	143.97 mL
0.5 mM	2.88 mL	14.4 mL	28.79 mL
1 mM	1.44 mL	7.2 mL	14.4 mL
5 mM	0.29 mL	1.44 mL	2.88 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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