EGFR Inhibitor

Name: EGFR Inhibitor
SKU: A13673

目录号: A13673

EGFR 抑制剂

EGFR Inhibitor Chemical Structure

CAS NO. 879127-07-8

EGFR inhibitor是一种可透过细胞的4,6-二取代嘧啶化合物，可选择性抑制EGFR激酶，在体外的IC50值为21 nM，可阻断细胞中的受体自身磷酸化。

库存：现货

规格	价格	数量
5 mg	￥ 1,800.00
10 mg	￥ 3,000.00
25 mg	￥ 6,000.00

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生物活性

EGFR inhibitor是一种可透过细胞的4,6-二取代嘧啶化合物，可选择性抑制EGFR激酶，在体外的IC50值为21 nM，可阻断细胞中的受体自身磷酸化。

溶解度 *

In vitro	DMSO	79 mg/mL (191.09 mM)
	Water	<1 mg/mL
	Ethanol	2 mg/mL (4.83 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.19 mL	120.95 mL	241.9 mL
0.5 mM	4.84 mL	24.19 mL	48.38 mL
1 mM	2.42 mL	12.09 mL	24.19 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13673
作用机制	Inhibitor (抑制剂)
M. Wt	413.4
Formula	C21H18F3N5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	879127-07-8
Synonyms	Epidermal Growth Factor Receptor Inhibitor
SMILES	C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)NC4=CC=CC(=C4)C(F)(F)F