EHop-016
目录号: A12740
Rac GTPase 抑制剂
EHop-016 是一种强效且特异性的抑制剂,专门针对 Rac1 和 Rac3 GTPase 活性,能够抑制 Vav2 与 Rac 的相互作用、Rac 激活的 PAK1、lamellipodia 形成以及细胞迁移。
Discription | EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration. | |||||
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Targets |
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Cell Research |
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目录号 | A12740 |
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分子式 | C25H30N6O |
分子量 | 430.55 |
CAS号 | 1380432-32-5 |
SMILES | CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51 |
其他名称 | EHop016 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 83 mg/mL (192.77 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.23 mL | 116.13 mL | 232.26 mL |
0.5 mM | 4.65 mL | 23.23 mL | 46.45 mL |
1 mM | 2.32 mL | 11.61 mL | 23.23 mL |
5 mM | 0.46 mL | 2.32 mL | 4.65 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2