EHop-016

目录号: A12740

Rac GTPase Inhibitor

EHop-016

EHop-016 Chemical Structure

CAS NO. 1380432-32-5

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
100 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 890.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.
靶点信息
Rac1 (MDA-MB-435, MDA-MB-231 cells)
1.1 μM
In vitro (25°C) DMSO 83 mg/mL (192.77 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.13 mL 232.26 mL
0.5 mM 4.65 mL 23.23 mL 46.45 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12740
作用机制 Inhibitor (抑制剂)
M. Wt 430.55
Formula C25H30N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1380432-32-5
Synonyms EHop016
SMILES CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51

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