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Rac GTPase 抑制剂

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产品目录号: A12740


产品名 目录号 价格 数量
EHop-016 10mg A12740-10
¥ 700.00
EHop-016 25mg A12740-25
¥ 1,500.00
EHop-016 50mg A12740-50
¥ 2,500.00
EHop-016 100mg A12740-100
¥ 4,000.00
EHop-016 10mM * 1mL in DMSO A12740-10mM-D
¥ 890.00



EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A12740
Mechanism of action Inhibitor
分子量 430.55
化学分子式 C25H30N6O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1380432-32-5
Synonyms EHop016
化学名称 N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine


EHop-016 is a potent and specific inhibitor of Rac1 and Rac3 GTPase activity that inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration.
Rac1 (MDA-MB-435, MDA-MB-231 cells)
1.1 μM


Solubility (25°C) * In vitro DMSO 86 mg/mL (199.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.13 mL 232.26mL
0.5 mM 4.65 mL 23.23 mL 46.45 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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