EHT 1610

Name: EHT 1610
SKU: A12586
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A12586

DYRK 抑制剂

EHT 1610 是一种高效且具有选择性的双特异性酪氨酸磷酸化调节激酶（DYRK）抑制剂，对 DYRK1A 和 DYRK1B 的 IC₅₀ 分别为 0.36 nM 和 0.59 nM。该化合物表现出显著的抗白血病活性，能够调控细胞周期进程并诱导细胞凋亡。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
5mg	¥1,505.00	现货
10mg	¥2,275.00	现货
25mg	¥3,710.00	现货
50mg	¥5,075.00	现货
100mg	¥6,895.00	现货
200mg	¥9,275.00	现货
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Data Sheet

SDS

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生物活性

Discription

EHT 1610 is a highly potent and selective inhibitor of dual-specificity tyrosine-phosphorylation-regulated kinases (DYRK), exhibiting IC₅₀ values of 0.36 nM for DYRK1A and 0.59 nM for DYRK1B. EHT 1610 demonstrates significant antileukemic activity, associated with modulation of cell cycle progression and induction of apoptotic pathways in target cells.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12586
分子式	C18H14FN5O2S
分子量	383.4
CAS号	1425945-60-3
SMILES	N=C(C(S1)=NC2=C1C3=C(NC4=CC=C(OC)C=C4F)N=CN=C3C=C2)OC
其他名称	EHT1610
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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