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Elafibranor是过氧化物酶体增殖物激活的受体-α和-δ的激动剂，可诱导非酒精性脂肪性肝炎消退，而不会使纤维化恶化。
| In vitro | DMSO | 74 mg/mL (192.46 mM) | |
| Water | Insoluble | ||
| Ethanol | 74 mg/mL (192.46 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.01 mL | 130.04 mL | 260.08 mL |
| 0.5 mM | 5.2 mL | 26.01 mL | 52.02 mL |
| 1 mM | 2.6 mL | 13 mL | 26.01 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.2 mL |
*The above data is based on the productmolecular weight 384.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15454 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 384.49 |
| Formula | C22H24O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 923978-27-2 |
| Synonyms | GFT505, GFT-505, GFT 505 |
| SMILES | CC1=CC(=CC(=C1OC(C)(C)C(=O)O)C)C=CC(=O)C2=CC=C(C=C2)SC |
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