产品详情
Elbasvir (MK-8742)是一种NS5A抑制剂,可预防丙型肝炎病毒RNA复制和病毒体组装。根据基因型,EC50的中值范围为0.2至3600 pmol/L。
In vitro | DMSO | 99 mg/mL (112.24 mM) | |
Water | Insoluble | ||
Ethanol | 99 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.34 mL | 56.69 mL | 113.38 mL |
0.5 mM | 2.27 mL | 11.34 mL | 22.68 mL |
1 mM | 1.13 mL | 5.67 mL | 11.34 mL |
5 mM | 0.23 mL | 1.13 mL | 2.27 mL |
*The above data is based on the productmolecular weight 882.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16855 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 882.02 |
Formula | C49H55N9O7 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1370468-36-2 |
Synonyms | MK8742, MK 8742 |
SMILES | O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)C1C(N2)=NC=C2C(C=C3)=CC4=C3N([C@H](C5=CC=CC=C5)OC6=C7C=CC(C8=CN=C([C@@H]9CCCN9C([C@@H](NC(OC)=O)C(C)C)=O)N8)=C6)C7=C4 |
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