Eldelumab (BMS-936557) is a human monoclonal antibody of the IgG1 subtype designed to selectively target and neutralize CXCL10 (IP-10). By binding to CXCL10, Eldelumab effectively inhibits CXCL10-induced calcium flux and cellular migration. This antibody is particularly useful in research focused on autoimmune and auto-inflammatory disorders, including rheumatoid arthritis, ulcerative colitis, and Crohn's disease, providing a valuable tool for elucidating the role of CXCL10 in these conditions.
Eldelumab (BMS-936557) is a human monoclonal antibody of the IgG1 subtype designed to selectively target and neutralize CXCL10 (IP-10). By binding to CXCL10, Eldelumab effectively inhibits CXCL10-induced calcium flux and cellular migration. This antibody is particularly useful in research focused on autoimmune and auto-inflammatory disorders, including rheumatoid arthritis, ulcerative colitis, and Crohn's disease, providing a valuable tool for elucidating the role of CXCL10 in these conditions.
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