Elexacaftor
            目录号: A20094
    
            CFTR modulator
    
								
							Elexacaftor(VX-445,Compound 1)是囊性纤维化跨膜传导调节因子(CFTR)的调节剂。
        | Discription | Elexacaftor (VX-445, Compound 1) is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR). | 
|---|
| 目录号 | A20094 | 
|---|---|
| 分子式 | C26H34F3N7O4S | 
| 分子量 | 597.65 | 
| CAS号 | 2216712-66-0 | 
| SMILES | CC1(C)C[C@H](C)CN1C2=C(C(NS(C3=CN(C)N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2 | 
| 其他名称 | VX-445, VX445?? | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.   | 
				
| In vitro | DMSO | 99 mg/mL (165.65 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| 
																	  *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.  | 
																|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 16.73 mL | 83.66 mL | 167.32 mL | 
| 0.5 mM | 3.35 mL | 16.73 mL | 33.46 mL | 
| 1 mM | 1.67 mL | 8.37 mL | 16.73 mL | 
| 5 mM | 0.33 mL | 1.67 mL | 3.35 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2