产品详情
Elobixibat is a potent ileal bile acid transporter (IBAT) inhibitor with IC50 values of 0.53 ?? 0.17 nM, 0.13 ?? 0.03 nM, and 5.8 ?? 1.6 nM for human IBAT, mouse IBAT, and canine IBAT.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.37 mL | 71.85 mL | 143.7 mL |
0.5 mM | 2.87 mL | 14.37 mL | 28.74 mL |
1 mM | 1.44 mL | 7.19 mL | 14.37 mL |
5 mM | 0.29 mL | 1.44 mL | 2.87 mL |
*The above data is based on the productmolecular weight 695.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20984 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 695.89 |
Formula | C36H45N3O7S2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 439087-18-0 |
Synonyms | A 3309, A3309, A-3309; AZD 7806, AZD7806, AZD-7806 |
SMILES | O=C(O)CNC([C@@H](C1=CC=CC=C1)NC(COC2=C(SC)C=C(C3=C2)N(C4=CC=CC=C4)CC(CCCC)(CCCC)CS3(=O)=O)=O)=O |
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