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ELR510444

Microtubule Disruptor

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产品目录号: A15455

库存状态:中国现货中国现货

产品名 目录号 价格 数量
ELR510444 10mg A15455-10
¥ 1,200.00
ELR510444 25mg A15455-25
¥ 2,500.00
ELR510444 50mg A15455-50
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

ELR510444

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Chemical Information

目录号 A15455
Mechanism of action
分子量 368.47
化学分子式 C19H16N2O2S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1233948-35-0
Synonyms ELR-510444, ELR 510444
SMILES code CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1
化学名称 N-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide

生物活性

Description
ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in ??III-tubulin-overexpressing cell lines.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.7 mL 271.39mL
0.5 mM 5.43 mL 27.14 mL 54.28 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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