Emactuzumab (RG 7155) is a highly specific monoclonal antibody designed to inhibit the activation of the colony-stimulating factor 1 receptor (CSF1R). It exhibits a high affinity for CSF-1R with a dissociation constant (Ki) of 0.2 nM, effectively blocking CSF-1R dimerization. This antibody is primarily utilized in research focused on various diseases, including diffuse-type tenosynovial giant cell tumor (dt-GCT). Emactuzumab serves as a crucial tool for elucidating the role of CSF1R in disease pathology and for the development of therapeutic strategies targeting this receptor.
Emactuzumab (RG 7155) is a highly specific monoclonal antibody designed to inhibit the activation of the colony-stimulating factor 1 receptor (CSF1R). It exhibits a high affinity for CSF-1R with a dissociation constant (Ki) of 0.2 nM, effectively blocking CSF-1R dimerization. This antibody is primarily utilized in research focused on various diseases, including diffuse-type tenosynovial giant cell tumor (dt-GCT). Emactuzumab serves as a crucial tool for elucidating the role of CSF1R in disease pathology and for the development of therapeutic strategies targeting this receptor.
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