Emricasan
目录号: A11394
Caspase 抑制剂
Emricasan 是一种首创的caspase抑制剂,目前正在临床试验中,用于治疗肝脏疾病。
| Discription | Emricasan is a first-in-class caspase inhibitor in clinical trials for the treatment of liver diseases. | ||
|---|---|---|---|
| Targets |
|
| 目录号 | A11394 |
|---|---|
| 分子式 | C26H27F4N3O7 |
| 分子量 | 569.5 |
| CAS号 | 254750-02-2 |
| SMILES | CC(C(=O)NC(CC(=O)O)C(=O)COC1=C(C(=CC(=C1F)F)F)F)NC(=O)C(=O)NC2=CC=CC=C2C(C)(C)C |
| 其他名称 | IDN-6556, IDN6556, IDN 6556, PF 03491390, PF-03491390, PF03491390 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 97 mg/mL (170.32 mM) | |
| Water | Insoluble | ||
| Ethanol | 97 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.56 mL | 87.8 mL | 175.59 mL |
| 0.5 mM | 3.51 mL | 17.56 mL | 35.12 mL |
| 1 mM | 1.76 mL | 8.78 mL | 17.56 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2