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EMT inhibitor-2 inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.26 mL | 106.28 mL | 212.55 mL |
| 0.5 mM | 4.25 mL | 21.26 mL | 42.51 mL |
| 1 mM | 2.13 mL | 10.63 mL | 21.26 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.25 mL |
*The above data is based on the productmolecular weight 470.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18568 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 470.47 |
| Formula | C24H26N2O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2232228-60-1 |
| SMILES | COC1=C(O)C2=C(OC(C3=CC=C(OC)C(OC)=C3)=CC2=O)C=C1OCCN(C4)CCNC4=O |
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