Enarodustat
目录号: A19214
prolyl hydroxylase 抑制剂
Enarodustat 是一种强效且可口服的因子脯氨酸羟化酶抑制剂,其 EC50 为 0.22 μM;Enarodustat 已进入用于治疗肾性贫血的临床试验阶段。
| Discription | Enarodustat is a potent and orally active factor prolyl hydroxylase inhibitor, with an EC50 of 0.22 μM; Enarodustat has entered clinical trial for renal anemia. |
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| 目录号 | A19214 |
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| 分子式 | C17H16N4O4 |
| 分子量 | 340.33 |
| CAS号 | 1262132-81-9 |
| SMILES | O=C(C(C1=NC=NN1C(CCC2=CC=CC=C2)=C3)=C3O)NCC(O)=O |
| 其他名称 | JTZ-951, JTZ 951, JTZ951 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 67 mg/mL (196.86 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (5.87 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.38 mL | 146.92 mL | 293.83 mL |
| 0.5 mM | 5.88 mL | 29.38 mL | 58.77 mL |
| 1 mM | 2.94 mL | 14.69 mL | 29.38 mL |
| 5 mM | 0.59 mL | 2.94 mL | 5.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2