Eniluracil
目录号: A21548
dihydropyrimidine dehydrogenase 抑制剂
Eniluracil(5-乙炔基尿嘧啶),一种尿嘧啶类似物和一种基于机制的不可逆抑制剂,针对二氢嘧啶脱氢酶(DPD),能够将5-氟尿嘧啶(5-FU)的口服生物利用度提高到100%,从而促进均匀吸收和可预测的毒性。
| Discription | Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity. |
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| 目录号 | A21548 |
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| 分子式 | C6H4N2O2 |
| 分子量 | 136.11 |
| CAS号 | 59989-18-3 |
| SMILES | O=C(N1)NC=C(C#C)C1=O |
| 其他名称 | 5-Ethynyluracil; GW776C85, GW 776C85, GW-776C85 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2