Entacapone
目录号: A10355
COMT 抑制剂
Entacapone 是一种特异性强、作用于外周的儿茶酚-O-甲基转移酶（COMT）抑制剂，其半抑制浓度（IC50）为151纳摩尔，用于治疗帕金森病（PD）。
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生物活性
| Discription | Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment. | |||||
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| Cell Research |
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产品信息
| 目录号 | A10355 |
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| 分子式 | C14H15N3O5 |
| 分子量 | 305.29 |
| CAS号 | 130929-57-6 |
| SMILES | O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 54 mg/mL (176.88 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.76 mL | 163.78 mL | 327.56 mL |
| 0.5 mM | 6.55 mL | 32.76 mL | 65.51 mL |
| 1 mM | 3.28 mL | 16.38 mL | 32.76 mL |
| 5 mM | 0.66 mL | 3.28 mL | 6.55 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 130929-57-6 | 130929-57-6 供应商 | 130929-57-6 花费 | 130929-57-6 生产商 | 订购 130929-57-6 | 130929-57-6 代理商