Entrectinib

Name: Entrectinib
SKU: A15801
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A15801

TRK, ROS1, ALK 抑制剂

1 篇发表文献

Entrectinib，也被称为 RXDX-101 和 NMS-E628，是一种口服小分子抑制剂，针对 TrkA、TrkB 和 TrkC，以及 ROS1 和 ALK，具有高效性和选择性。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥315.00	现货
10mg	¥525.00	现货
25mg	¥735.00	现货
50mg	¥1,155.00	现货
100mg	¥2,030.00	现货
500mg	¥5,040.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Entrectinib发表的1篇文献

Angelina T Regua, .et al. , Cancer Lett, 2024, Jun 7:597:217023 PMID: 38852701

生物活性

Discription

Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15801
分子式	C31H34F2N6O2
分子量	560.64
CAS号	1108743-60-7
SMILES	CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6
其他名称	RXDX-101, RXDX-101, RXDX-101, NMS E628, NMS-E628, NMSE628
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (158.74 mM)
	Water	Insoluble
	Ethanol	67 mg/mL (119.5 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.84 mL	89.18 mL	178.37 mL
0.5 mM	3.57 mL	17.84 mL	35.67 mL
1 mM	1.78 mL	8.92 mL	17.84 mL
5 mM	0.36 mL	1.78 mL	3.57 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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