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Epertinib

目录号: A13777
EGFR/HER2/HER4 抑制剂
Epertinib 是一种强效的、口服的、可逆的、选择性的酪氨酸激酶抑制剂,针对 EGFRHER2HER4,其半抑制浓度(IC50s)分别为 1.48 nM、7.15 nM 和 2.49 nM。Epertinib 显示出强大的抗肿瘤活性。
Grouped product items
规格 价格 库存 数量
5mg
¥2,520.00
现货
10mg
¥4,900.00
现货
25mg
¥9,485.00
现货
50mg
¥10,255.00
现货
100mg
¥17,465.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Epertinib is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity.
Targets
Target Value
产品信息
目录号 A13777
分子式 C30H27ClFN5O3
分子量 560.02
CAS号 908305-13-5
SMILES CC#C/C(C1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1)=N\OC[C@@H]5NCCOC5
其他名称 S-22611, S22611, S 22611
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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