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Epirubicin

促销

Topoisomerase 抑制剂

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产品目录号: A12409

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Epirubicin 10mg A12409-10
¥ 750.00
Epirubicin 25mg A12409-25
¥ 1,500.00
Epirubicin 50mg A12409-50
¥ 2,600.00
Epirubicin 100mg A12409-100
¥ 4,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Epirubicin is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin that exhibits reduced cardiotoxicity. Epirubicin’s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).

Epirubicin

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Epirubicin 发表的文献 (1)
  • Xiu-wu Pan, .et al. Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy, Oncol Rep, 2016, Jan;35(1):334-42 PMID: 26496799

Chemical Information

目录号 A12409
Mechanism of action Inhibitor
分子量 543.52
化学分子式 C27H29NO11
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 56420-45-2
Synonyms N/A
SMILES code C[C@H]1[C@@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
化学名称 (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione

生物活性

Description
Epirubicin is a cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin that exhibits reduced cardiotoxicity. Epirubicin’s antitumor actions are mediated by targeting and inhibiting Topo II (topoisomerase II).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.99 mL 183.99mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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