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Epoxomicin

Proteasome 抑制剂

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产品目录号: A12730

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Epoxomicin 2mg A12730-2
¥ 1,200.00
Epoxomicin 5mg A12730-5
¥ 2,500.00
Epoxomicin 10mg A12730-10
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome.

Epoxomicin

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Chemical Information

目录号 A12730
Mechanism of action Inhibitor
分子量 554.7
化学分子式 C28H50N4O7
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 134381-21-8
Synonyms BU-4061T
SMILES code C1=CC=C2C(=C1)C(=CC(=N2)NC(=O)C3=CC(=CC(=N3)C(=O)NC4=NC5=CC=CC=C5C(=C4)OCCN)OCCN)OCCN
化学名称 (2S,3S)-2-[[(2S,3S)-2-[acetyl(methyl)amino]-3-methylpentanoyl]amino]-N-[(2S,3R)-3-hydroxy-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxobutan-2-yl]-3-methylpentanamide

生物活性

Description
Epoxomicin is a potent anti-tumor agent isolated from Actinomycetes that is used as a selective and irreversible inhibitor of the 20S proteasome.
Targets
20S proteasome

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.03 mL 90.14 mL 180.28mL
0.5 mM 3.61 mL 18.03 mL 36.06 mL
1 mM 1.8 mL 9.01 mL 18.03 mL
5 mM 0.36 mL 1.8 mL 3.61 mL

*The above data is based on the productmolecular weight 554.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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