EPZ011989

目录号: A15544

EZH2 抑制剂

EPZ011989 Chemical Structure

CAS NO. 1598383-40-4

EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 850.00
25 mg
¥ 1,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.51 mL 82.53 mL 165.07 mL
0.5 mM 3.3 mL 16.51 mL 33.01 mL
1 mM 1.65 mL 8.25 mL 16.51 mL
5 mM 0.33 mL 1.65 mL 3.3 mL

*The above data is based on the productmolecular weight 605.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15544
MECHANISM OF ACTION Inhibitor
M. Wt 605.81
Formula C35H51N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1598383-40-4
Synonyms EPZ-011989, EPZ 011989
SMILES CCN(C1CCC(CC1)N(C)CCOC)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C#CCN4CCOCC4

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