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PRMT6 抑制剂

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产品目录号: A16377


产品名 目录号 价格 数量
EPZ020411 5mg A16377-5
¥ 1,600.00
EPZ020411 10mg A16377-10
¥ 2,800.00
EPZ020411 50mg A16377-50
¥ 8,400.00



EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.





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Chemical Information

目录号 A16377
Mechanism of action Inhibitor
分子量 442.59
化学分子式 C25H38N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1700663-41-7
Synonyms EPZ-020411
化学名称 N1,N2-dimethyl-N1-((3-(4-((1r,3r)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutoxy)phenyl)-1H-pyrazol-4-yl)methyl)ethane-1,2-diamine


EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.59 mL 112.97 mL 225.94mL
0.5 mM 4.52 mL 22.59 mL 45.19 mL
1 mM 2.26 mL 11.3 mL 22.59 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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