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EPZ031686

SMYD3/ MEKK2 抑制剂

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产品目录号: A16375

库存状态:中国现货中国现货

产品名 目录号 价格 数量
EPZ031686 1mg A16375-1
¥ 1,200.00
EPZ031686 2mg A16375-2
¥ 2,000.00
EPZ031686 5mg A16375-5
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

EPZ031686 is a noncompetitive inhibitor for SMYD3 and MEKK2 with a Ki=1.2 and 1.1 nM respectively.

EPZ031686

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Chemical Information

目录号 A16375
Mechanism of action Inhibitor
分子量 591.09
化学分子式 C26H34ClF3N4O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1808011-22-4
Synonyms EPZ-031686, EPZ 031686
SMILES code ClC1=CC(N2)=C(CC2=O)C=C1C(N[C@@]3([H])C[C@@](N4S(CC(CC5)CCN5CCCC(F)(F)F)(=O)=O)([H])CC[C@@]4([H])C3)=O
化学名称 6-chloro-2-oxo-N-((1R,3r,5S)-8-(((1-(4,4,4-trifluorobutyl)piperidin-4-yl)methyl)sulfonyl)-8-azabicyclo[3.2.1]octan-3-yl)indoline-5-carboxamide

生物活性

Description
EPZ031686 is a noncompetitive inhibitor for SMYD3 and MEKK2 with a Ki=1.2 and 1.1 nM respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.92 mL 84.59 mL 169.18mL
0.5 mM 3.38 mL 16.92 mL 33.84 mL
1 mM 1.69 mL 8.46 mL 16.92 mL
5 mM 0.34 mL 1.69 mL 3.38 mL

*The above data is based on the productmolecular weight 591.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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