Erastin

目录号: A13822

VDAC 抑制剂

Erastin

Erastin Chemical Structure

CAS NO. 571203-78-6

Erastin是一种细胞可渗透的哌嗪基-喹唑啉酮化合物,在具有H-Ras突变的细胞中表现出癌基因选择性致死性。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 1,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Erastin是一种细胞可渗透的哌嗪基-喹唑啉酮化合物,在具有H-Ras突变的细胞中表现出癌基因选择性致死性。
靶点信息
Ferroptosis
In vitro (25°C) DMSO 17 mg/mL (31.07 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+40%PEG 300+5%Tween80+ddH2O 1.66 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.4 mL 182.8 mL
0.5 mM 3.66 mL 18.28 mL 36.56 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 547.04. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13822
作用机制 Inhibitor (抑制剂)
M. Wt 547.04
Formula C30H31ClN4O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 571203-78-6
SMILES CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl

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