Erastin

Name: Erastin
SKU: A13822
Price: 245 CNY
Rating: 5 (8 reviews)

目录号: A13822

VDAC 抑制剂

8 篇发表文献

Erastin 是一种细胞渗透性的哌嗪基喹唑啉酮化合物，对带有 H-Ras 突变的细胞表现出 癌基因选择性致死性。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥455.00	现货
10mg	¥805.00	现货
25mg	¥1,715.00	现货
50mg	¥2,415.00	现货
*10mM 1mL in DMSO**	¥945.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Erastin发表的8篇文献

Mao Yang, .et al. , Biochem Biophys Res Commun, 2025, Sep 5:784:152599 PMID: 40972362

Xuejie Huan, .et al. , Neurosci Bull, 2024, Dec 12 PMID: 39666195

Filiz Bakar-Ates, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2024, Oct 11 PMID: 39392483

Filiz Bakar-Ates, .et al. , Toxicol In Vitro, 2024, Feb:94:105732 PMID: 37956772

Sureya Nijiati, .et al. , Mol Pharm, 2023, Oct 2;20(10):5185-5194 PMID: 37711135

Erva Ozkan, .et al. , Life Sci, 2023, Jan 1;312:121222 PMID: 36442526

Yuki Shibata, .et al. , Biochem Biophys Rep, 2021, Feb 24;26 PMID: 33681481

Shibata Y, .et al. , PLoS One, 2019, Dec 4;14(12):e0225931 PMID: 31800616

生物活性

Discription

Erastin is a cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality in cells with H-Ras mutations.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13822
分子式	C30H31ClN4O4
分子量	547.04
CAS号	571203-78-6
SMILES	CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	17 mg/mL (31.07 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG 300+5%Tween80+ddH2O	1.66 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.28 mL	91.4 mL	182.8 mL
0.5 mM	3.66 mL	18.28 mL	36.56 mL
1 mM	1.83 mL	9.14 mL	18.28 mL
5 mM	0.37 mL	1.83 mL	3.66 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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