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ESI-05

目录号: A18644
EPAC2 拮抗剂
ESI-05(NSC 116966)是一种特异性的EPAC2(通过cAMP直接激活的交换蛋白2)拮抗剂,其IC50为0.4 μM。ESI-05(NSC 116966)抑制cAMP介导的EPAC2激活以及EAPC2介导的Rap1激活。
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规格 价格 库存 数量
2mg
¥175.00
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5mg
¥315.00
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10mg
¥595.00
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25mg
¥1,120.00
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50mg
¥1,925.00
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100mg
¥3,325.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用ESI-05发表的1篇文献
  • Yuri A Blednov, .et al. , Neuropharmacology, 2024, Jun 13:257:110035 PMID: 38876310
  • 生物活性
    Discription ESI-05 (NSC 116966) is a specific antagonist of EPAC2 (exchange protein directly activated by cAMP 2), with an IC50 of 0.4 ?M. ESI-05 (NSC 116966) inhibits cAMP-mediated activation of EPAC2 as well as EAPC2 mediated Rap1 activation.
    产品信息
    目录号 A18644
    分子式 C16H18O2S
    分子量 274.37
    CAS号 5184-64-5
    SMILES O=S(C1=C(C)C=C(C)C=C1C)(C2=CC=C(C)C=C2)=O
    其他名称 ESI05, ESI 05
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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