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ETC-1002

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ACL 抑制剂 and AMPK activator

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产品目录号: A15815

库存状态:中国现货中国现货

产品名 目录号 价格 数量
ETC-1002 5mg A15815-5
¥ 800.00
ETC-1002 10mg A15815-10
¥ 1,200.00
ETC-1002 25mg A15815-25
¥ 2,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).

ETC-1002

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Chemical Information

目录号 A15815
Mechanism of action Activator, Inhibitor
分子量 344.49
化学分子式 C19H36O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 738606-46-7
Synonyms ESP-55016, ETC1002, ETC 1002
SMILES code CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O
化学名称 Bempedoic Acid

生物活性

Description
ETC-1002 is a novel, first-in-class, orally available, once-daily LDL-C lowering small molecule; activator of hepatic AMP-activated protein kinase (AMPK); also has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
Targets
AMPK

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.03 mL 145.14 mL 290.28mL
0.5 mM 5.81 mL 29.03 mL 58.06 mL
1 mM 2.9 mL 14.51 mL 29.03 mL
5 mM 0.58 mL 2.9 mL 5.81 mL

*The above data is based on the productmolecular weight 344.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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