Tinodasertib (ETC-206)
目录号: A19366
MNK1 and MNK2 抑制剂
ETC-206 是一种选择性的 MNK1 和 MNK2 抑制剂,其 IC50 分别为 64 nM 和 86 nM。
| Discription | ETC-206 is a selective MNK1 and MNK2 inhibitor with IC50s of 64 nM and 86 nM, respectively. | |||||
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| Cell Research |
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| 目录号 | A19366 |
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| 分子式 | C25H20N4O2 |
| 分子量 | 408.45 |
| CAS号 | 1464151-33-4 |
| SMILES | N#CC1=CC=C(C2=CN=C3C=CC(C4=CC=C(C(N5CCOCC5)=O)C=C4)=CN32)C=C1 |
| 其他名称 | ETC 206; ETC206 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 79 mg/mL (193.41 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.48 mL | 122.41 mL | 244.83 mL |
| 0.5 mM | 4.9 mL | 24.48 mL | 48.97 mL |
| 1 mM | 2.45 mL | 12.24 mL | 24.48 mL |
| 5 mM | 0.49 mL | 2.45 mL | 4.9 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2