Etoricoxib
目录号: A13770
COX-2 抑制剂
Etoricoxib 特异性地结合并抑制酶环氧合酶-2 (COX-2)，从而抑制花生四烯酸转化为前列腺素的过程。抑制 COX-2 可能诱导凋亡，并抑制肿瘤细胞增殖和血管生成。
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生物活性
| Discription | Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13770 |
|---|---|
| 分子式 | C18H15ClN2O2S |
| 分子量 | 358.84 |
| CAS号 | 202409-33-4 |
| SMILES | CC1=NC=C(C=C1)C2=NC=C(C=C2C3=CC=C(C=C3)S(=O)(=O)C)Cl |
| 其他名称 | Arcoxia, MK-663, MK-0663 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 70 mg/mL (195.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 46 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.87 mL | 139.34 mL | 278.68 mL |
| 0.5 mM | 5.57 mL | 27.87 mL | 55.74 mL |
| 1 mM | 2.79 mL | 13.93 mL | 27.87 mL |
| 5 mM | 0.56 mL | 2.79 mL | 5.57 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 202409-33-4 | 202409-33-4 供应商 | 202409-33-4 花费 | 202409-33-4 生产商 | 订购 202409-33-4 | 202409-33-4 代理商