ETP-46464

目录号: A13328

ATR inhibitor

ETP-46464 Chemical Structure

CAS NO. 1345675-02-6

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.

库存: 现货

规格 价格 数量
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
50 mg
¥ 5,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
Targets
mTOR ATR DNA-PK PI3Kα ATM
0.6 nM14 nM36 nM170 nM545 nM
In vitro DMSO 6 mg/mL (12.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.27 mL 212.53 mL
0.5 mM 4.25 mL 21.25 mL 42.51 mL
1 mM 2.13 mL 10.63 mL 21.25 mL
5 mM 0.43 mL 2.13 mL 4.25 mL

*The above data is based on the productmolecular weight 470.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13328
MECHANISM OF ACTION Inhibitor
M. Wt 470.52
Formula C30H22N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1345675-02-6
Synonyms ETP46464, ETP 46464
SMILES CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3COC2=O)C5=CC6=CC=CC=C6N=C5

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