Evacetrapib (LY2484595)

目录号: A11397

CETP inhibitor

Evacetrapib (LY2484595) Chemical Structure

CAS NO. 1186486-62-3

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,400.00
25 mg
¥ 5,000.00
50 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 2,110.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
靶点信息
CETP
5.5 nM
In vitro (25°C) DMSO 12.8 mg/mL (20.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol 12.8 mg/mL (20.04 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.66 mL 78.29 mL 156.58 mL
0.5 mM 3.13 mL 15.66 mL 31.32 mL
1 mM 1.57 mL 7.83 mL 15.66 mL
5 mM 0.31 mL 1.57 mL 3.13 mL

*The above data is based on the productmolecular weight 638.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11397
MECHANISM OF ACTION Inhibitor
M. Wt 638.65
Formula C31H36F6N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1186486-62-3
Synonyms LY2484595, LY-2484595, LY 2484595
SMILES CC1=CC(=C2C(=C1)[C@H](CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C

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