Everolimus (RAD001)

Name: Everolimus (RAD001)
SKU: A10374
Price: 210 CNY
Rating: 5 (10 reviews)

目录号: A10374

mTOR 抑制剂

10 篇发表文献

Everolimus（RAD-001）是西罗莫司的40-O-(2-羟乙基)衍生物，其作用方式与西罗莫司类似，均为mTOR抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥315.00	现货
25mg	¥490.00	现货
50mg	¥630.00	现货
100mg	¥805.00	现货
250mg	¥1,400.00	现货
500mg	¥2,135.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Everolimus (RAD001)发表的10篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Ming-Chun Hung, .et al. , Cell Biosci, 2022, 12: 122 PMID: 35918763

Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890

Gabriela Torres-Flores, .et al. , Adv Polym Technol, 2020, ID 5462949

Takaaki Fujimura, .et al. , Cancer Biol Ther, 2020, Sep 1;21(9):863-870 PMID: 32835580

BD Henriksbo, .et al. , Am J Physiol Endocrinol Metab, 2020, Jul 1;319(1):E110-E116 PMID: 32421368

Hiroshi Fukamachi, .et al. , J Exp Clin Cancer Res, 2019, 38:127 PMID: 30866995

Nachi Namatame, .et al. , Oncotarget, 2018, Oct 12; 9(80): 35141-35161 PMID: 30416685

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Rieko Ohki, .et al. , Proc Natl Acad Sci U S A, 2014, 111(23): E2404-E2413 PMID: 24912192

生物活性

Discription

Everolimus (RAD-001) is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an mTOR inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10374
分子式	C53H83NO14
分子量	958.2
CAS号	159351-69-6
SMILES	C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC
其他名称	SDZ-RAD, Certican, Zortress, Afinitor
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	91 mg/mL (94.97 mM)
	Water	Insoluble
	Ethanol	6 mg/mL (6.26 mM)
In vivo	30% Propylene glycol (dissolve first)+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.44 mL	52.18 mL	104.36 mL
0.5 mM	2.09 mL	10.44 mL	20.87 mL
1 mM	1.04 mL	5.22 mL	10.44 mL
5 mM	0.21 mL	1.04 mL	2.09 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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