Evista (Raloxifene HCl)
目录号: A10375
Raloxifene 是一种口服选择性雌激素受体调节剂(SERM),对骨骼具有雌激素作用,对子宫和乳腺具有抗雌激素作用。它用于预防绝经后妇女的骨质疏松症。
| Discription | Raloxifene is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women. | ||
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| 目录号 | A10375 |
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| 分子式 | C28H28ClNO4S |
| 分子量 | 510 |
| CAS号 | 82640-04-8 |
| SMILES | C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 90 mg/mL (176.45 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% methylcellulose | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.61 mL | 98.04 mL | 196.08 mL |
| 0.5 mM | 3.92 mL | 19.61 mL | 39.22 mL |
| 1 mM | 1.96 mL | 9.8 mL | 19.61 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2