Evobrutinib
目录号: A16824
BTK 抑制剂
Evobrutinib 是一种高度选择性的 BTK 抑制剂,其 IC50 为 37.9 nM。它具有潜在的抗肿瘤活性。
Discription | Evobrutinib is a highly selective BTK inhibitor with an IC50 of 37.9 nM. It has potential anti-neoplastic activity. | |||||
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Cell Research |
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目录号 | A16824 |
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分子式 | C25H27N5O2 |
分子量 | 429.51 |
CAS号 | 1415823-73-2 |
SMILES | C=CC(N1CCC(CNC2=NC=NC(N)=C2C3=CC=C(OC4=CC=CC=C4)C=C3)CC1)=O |
其他名称 | M-2951; M 2951; M2951; MSC-2364447C; MSC 2364447C; MSC2364447C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 76 mg/mL (176.94 mM) | |
Water | Insoluble | ||
Ethanol | 9 mg/mL (20.95 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.28 mL | 116.41 mL | 232.82 mL |
0.5 mM | 4.66 mL | 23.28 mL | 46.56 mL |
1 mM | 2.33 mL | 11.64 mL | 23.28 mL |
5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2