EX 527 (Selisistat)

目录号: A10377

SIRT1 inhibitor

EX 527 (Selisistat) Chemical Structure

CAS NO. 49843-98-3

EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with IC50 of 38 nM in a cell-free assay.

库存: 现货

规格 价格 数量
5 mg
¥ 250.00
10 mg
¥ 400.00
25 mg
¥ 700.00
100 mg
¥ 2,000.00
10mM * 1mL in DMSO
¥ 710.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with IC50 of 38 nM in a cell-free assay.
Targets
SIRT1 (Cell-free assay)
38 nM
In vitro (25°C) DMSO 50 mg/mL (201.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol 18 mg/mL (72.37 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.21 mL 201.05 mL 402.09 mL
0.5 mM 8.04 mL 40.21 mL 80.42 mL
1 mM 4.02 mL 20.1 mL 40.21 mL
5 mM 0.8 mL 4.02 mL 8.04 mL

*The above data is based on the productmolecular weight 248.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10377
MECHANISM OF ACTION Inhibitor
M. Wt 248.7
Formula C13H13ClN2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 49843-98-3
Synonyms EX527, EX-527
SMILES C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N

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