Exatecan mesylate

目录号: A11231

Topoisomerase I inhibitor

Exatecan mesylate

Exatecan mesylate Chemical Structure

CAS NO. 171335-80-1

Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.

库存: 缺货

规格 价格
10 mg
¥ 6,000.00
25 mg
¥ 12,000.00
50 mg
¥ 20,000.00
100 mg
¥ 35,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.81 mL 94.06 mL 188.11 mL
0.5 mM 3.76 mL 18.81 mL 37.62 mL
1 mM 1.88 mL 9.41 mL 18.81 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 531.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11231
MECHANISM OF ACTION Inhibitor
M. Wt 531.6
Formula C25H26FN3O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 171335-80-1
Synonyms DX 8951, DX8951
SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O

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