Exemestane
目录号: A10378
Aromatase 抑制剂
Exemestane 是一种口服类固醇芳香化酶抑制剂,用于治疗绝经后妇女的ER阳性乳腺癌,通常与手术和/或放疗联合使用。
| Discription | Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women. | |||||
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| 目录号 | A10378 |
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| 分子式 | C20H24O2 |
| 分子量 | 296.4 |
| CAS号 | 107868-30-4 |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C |
| 其他名称 | Aromasin |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 52 mg/mL (175.43 mM) | |
| Water | Insoluble | ||
| Ethanol | 15 mg/mL (50.6 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.74 mL | 168.69 mL | 337.38 mL |
| 0.5 mM | 6.75 mL | 33.74 mL | 67.48 mL |
| 1 mM | 3.37 mL | 16.87 mL | 33.74 mL |
| 5 mM | 0.67 mL | 3.37 mL | 6.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2