FABP4 Inhibitor

Name: FABP4 Inhibitor
SKU: A13404
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13404

FABP4 Inhibitor 是一种细胞渗透性的双苯基唑氧乙酸，它通过靶向其脂肪酸结合口袋（在使用1,8-ANS的竞争性结合实验中 Ki = < 2 nM）作为一种强效和选择性的脂肪细胞脂肪酸结合蛋白（aFABP/aP2）抑制剂，同时对肌肉和表皮FABP的亲和力较低（分别为 Ki = 250 nM 和 350 nM）。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,015.00	现货
50mg	¥1,470.00	现货
100mg	¥1,925.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription	FABP4 Inhibitor is a cell-permeable biphenylazolo-oxyacetate that acts as a potent and selective inhibitor of adipocyte Fatty-Acid-Binding Protein (aFABP/aP2) by targeting its fatty acid-binding pocket (Ki = < 2 nM in a competitive binding assay using 1,8-ANS), while exhibiting much lower affinity for muscle and epidermal FABP's (Ki = 250 nM and 350 nM, respectively).

产品信息

目录号	A13404
分子式	C31H26N2O3
分子量	474.55
CAS号	300657-03-8
SMILES	CCC1=C(C(=NN1C2=CC=CC=C2C3=CC(=CC=C3)OCC(=O)O)C4=CC=CC=C4)C5=CC=CC=C5
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (187.54 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (35.82 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.07 mL	105.36 mL	210.73 mL
0.5 mM	4.21 mL	21.07 mL	42.15 mL
1 mM	2.11 mL	10.54 mL	21.07 mL
5 mM	0.42 mL	2.11 mL	4.21 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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