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Fasudil HCl (HA-1077)

Fasudil HCl (HA-1077)

Name: Fasudil HCl (HA-1077)
SKU: A10381

目录号: A10381

ROCK 抑制剂

Product Citations (8)

Fasudil HCl (HA-1077) Chemical Structure

CAS NO. 105628-07-7

Fasudil HCl (HA-1077)是一种环状核苷酸依赖性蛋白激酶抑制剂和Rho相关激酶抑制剂（IC50 = 10.7μM）。

库存：现货

规格	价格	数量
250 mg	￥ 500.00
500 mg	￥ 750.00

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生物活性

Fasudil HCl (HA-1077)是一种环状核苷酸依赖性蛋白激酶抑制剂和Rho相关激酶抑制剂（IC50 = 10.7μM）。

靶点信息

ROCK2 (Cell-free assay)	PKA (Cell-free assay)	PKG (Cell-free assay)	PKC (Cell-free assay)	MLCK (Cell-free assay)
330 nM(Ki)	1.6 μM(Ki)	1.6 μM(Ki)	3.3 μM(Ki)	36 μM(Ki)

溶解度 *

In vitro (25°C)	DMSO	5 mg/mL (15.25 mM)
	Water	60 mg/mL (183.02 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.51 mL	152.53 mL	305.06 mL
0.5 mM	6.1 mL	30.51 mL	61.01 mL
1 mM	3.05 mL	15.25 mL	30.51 mL
5 mM	0.61 mL	3.05 mL	6.1 mL

*The above data is based on the productmolecular weight 327.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10381
作用机制	Inhibitor (抑制剂)
M. Wt	327.8
Formula	C14H17N3O2S.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	105628-07-7
Synonyms	AT-877
SMILES	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl