FG-4592 (Roxadustat)

目录号: A11237

HIF-PHs 抑制剂

FG-4592 (Roxadustat)

FG-4592 (Roxadustat) Chemical Structure

CAS NO. 808118-40-3

FG-4592 (Roxadustat)是一种用于CKD贫血的新型缺氧诱导因子脯氨酰羟化酶抑制剂。

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
50 mg
¥ 1,000.00
100 mg
¥ 1,300.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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FG-4592 (Roxadustat)是一种用于CKD贫血的新型缺氧诱导因子脯氨酰羟化酶抑制剂。
靶点信息
HIF α prolyl hydroxylase (Cell-free assay)
In vitro DMSO 70 mg/mL (198.67 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.38 mL 141.92 mL 283.85 mL
0.5 mM 5.68 mL 28.38 mL 56.77 mL
1 mM 2.84 mL 14.19 mL 28.38 mL
5 mM 0.57 mL 2.84 mL 5.68 mL

*The above data is based on the productmolecular weight 352.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11237
作用机制 Inhibitor (抑制剂)
M. Wt 352.3
Formula C19H16N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 808118-40-3
Synonyms FG4592, ASP1517
SMILES CC1=NC(=C(C2=C1C=C(C=C2)OC3=CC=CC=C3)O)C(=O)NCC(=O)O

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