|3.09 nM||4.3 nM||27 nM||45.3 nM|
|In vitro||DMSO||148 mg/mL (200.3 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||15.75 mL||78.77 mL||157.55 mL|
|0.5 mM||3.15 mL||15.75 mL||31.51 mL|
|1 mM||1.58 mL||7.88 mL||15.75 mL|
|5 mM||0.32 mL||1.58 mL||3.15 mL|
*The above data is based on the productmolecular weight 634.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
|Synonyms||FIIN2, FIIN 2|
R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angi…
Erdafitinib is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplas…
Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-a/β, and c-kit th…
FIIN-3 is a potent, selective, irreversible and the next-generation covalent FGFR inhibitor.
BGJ398 is a potent and selective inhibitor with potential antiangiogenic and antineoplastic activities of fibroblast growth factor receptor…
NVP-BGJ398 phosphate is a novel selective, pan-specific FGFR inhibitor with IC50 of 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respect…
PD173074 is a potent, cell permeable and ATP competitive inhibitor of FGFR and VEGFR.