Fimasartan

Name: Fimasartan
SKU: A17477

目录号: A17477

non-peptide angiotensin II receptor antagonist

Fimasartan Chemical Structure

CAS NO. 247257-48-3

Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys.

库存：现货

规格	价格	数量
5 mg	￥ 500.00
10 mg	￥ 800.00
50 mg	￥ 1,500.00
100 mg	￥ 2,400.00

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产品详情

生物活性

溶解度 *

In vitro	DMSO	97 mg/mL (193.36 mM)
	Ethanol	23 mg/mL (45.85 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.93 mL	99.67 mL	199.34 mL
0.5 mM	3.99 mL	19.93 mL	39.87 mL
1 mM	1.99 mL	9.97 mL	19.93 mL
5 mM	0.4 mL	1.99 mL	3.99 mL

*The above data is based on the productmolecular weight 501.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17477
作用机制	Antagonist (拮抗剂)
M. Wt	501.65
Formula	C27H31N7OS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	247257-48-3
Synonyms	BR-A657; BR A657; BRA657; BRA 657; Fimasartan. brand name: Kanarb.
SMILES	S=C(N(C)C)CC1=C(C)N=C(CCCC)N(CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C1=O