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Fisogatinib

Fisogatinib

Name: Fisogatinib
SKU: A20354

目录号: A20354

FGFR4 inhibitor

Fisogatinib Chemical Structure

CAS NO. 1707289-21-1

Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM.

库存：现货

规格	价格	数量
5 mg	￥ 1,350.00
10 mg	￥ 2,330.00
50 mg	￥ 6,900.00
100 mg	￥ 13,800.00

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生物活性

Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 5 nM.

溶解度 *

In vitro	DMSO	Warmed: 96 mg/mL (190.7 mM)
	Water	Insoluble
	Ethanol	Warmed: 2 mg/mL (3.97 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.87 mL	99.33 mL	198.66 mL
0.5 mM	3.97 mL	19.87 mL	39.73 mL
1 mM	1.99 mL	9.93 mL	19.87 mL
5 mM	0.4 mL	1.99 mL	3.97 mL

*The above data is based on the productmolecular weight 503.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20354
M. Wt	503.38
Formula	C24H24Cl2N4O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1707289-21-1
Synonyms	BLU-554, BLU554, BLU 554
SMILES	C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O