Fiztasovimab (NPC-21; EV2038) is a fully human IgG1?? monoclonal antibody designed to target human cytomegalovirus (hCMV). This antibody exhibits its neutralizing activity by specifically binding to antigenic domain 1 of glycoprotein B, which is located on the envelope of hCMV. Through this targeted interaction, Fiztasovimab effectively inhibits the cell-to-cell transmission of the virus, providing a crucial tool for research into viral pathogenesis and therapeutic intervention strategies.
Fiztasovimab (NPC-21; EV2038) is a fully human IgG1?? monoclonal antibody designed to target human cytomegalovirus (hCMV). This antibody exhibits its neutralizing activity by specifically binding to antigenic domain 1 of glycoprotein B, which is located on the envelope of hCMV. Through this targeted interaction, Fiztasovimab effectively inhibits the cell-to-cell transmission of the virus, providing a crucial tool for research into viral pathogenesis and therapeutic intervention strategies.
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