Flanvotumab (IMC-20D7S) is a human monoclonal antibody designed to specifically target tyrosinase-related protein 1 (TYRP1), which is predominantly expressed in melanocytes and melanoma cells. This antibody mediates its effects through the mechanism of antibody-dependent cell-mediated cytotoxicity (ADCC), engaging the body's natural killer cells to destroy tumor cells. Flanvotumab demonstrates significant anti-tumor activity and is well-tolerated, making it a valuable tool for research in melanoma therapeutics.
Flanvotumab (IMC-20D7S) is a human monoclonal antibody designed to specifically target tyrosinase-related protein 1 (TYRP1), which is predominantly expressed in melanocytes and melanoma cells. This antibody mediates its effects through the mechanism of antibody-dependent cell-mediated cytotoxicity (ADCC), engaging the body's natural killer cells to destroy tumor cells. Flanvotumab demonstrates significant anti-tumor activity and is well-tolerated, making it a valuable tool for research in melanoma therapeutics.
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