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FLT3-IN-3 is a potent FLT3 inhibitor with IC50s of 13 and 8 nM for FLT3 WT and FLT3 D835Y, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.38 mL | 101.91 mL | 203.82 mL |
| 0.5 mM | 4.08 mL | 20.38 mL | 40.76 mL |
| 1 mM | 2.04 mL | 10.19 mL | 20.38 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
*The above data is based on the productmolecular weight 490.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20172 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 490.64 |
| Formula | C27H38N8O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2229050-90-0 |
| SMILES | N[C@H](CC1)CC[C@@H]1NC2=NC3=C(N=CN3C4CCCC4)C(NC5=CC=C(CN6CCOCC6)C=C5)=N2 |
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