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Fludarabine Phosphate (Fludara)

Fludarabine Phosphate (Fludara)

Name: Fludarabine Phosphate (Fludara)
SKU: A10395

目录号: A10395

Fludarabine Phosphate (Fludara) Chemical Structure

CAS NO. 75607-67-9

Fludarabine Phosphate (Fludara)是一种用于治疗血液恶性肿瘤(血细胞癌，如白血病和淋巴瘤)的化疗药物。氟达拉滨通过干扰核糖核苷酸还原酶和dna聚合酶来抑制DNA合成。它对分裂细胞和静止细胞都有活性。

库存：现货

规格	价格	数量
10 mg	￥ 400.00
50 mg	￥ 1,200.00
100 mg	￥ 1,500.00
10mM * 1mL in DMSO	￥ 600.00

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产品详情

生物活性

靶点信息

DNA polymerase α	DNA polymerase δ
1.1 μM(Ki )	1.3 μM(Ki)

溶解度 *

In vitro (25°C)	DMSO	66 mg/mL (180.71 mM)
	Water	Warmed: 2 mg/mL (5.47 mM)
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.38 mL	136.91 mL	273.82 mL
0.5 mM	5.48 mL	27.38 mL	54.76 mL
1 mM	2.74 mL	13.69 mL	27.38 mL
5 mM	0.55 mL	2.74 mL	5.48 mL

*The above data is based on the productmolecular weight 365.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10395
M. Wt	365.2
Formula	C10H13FN5O7P
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	75607-67-9
SMILES	O[C@H]1[C@H](O)[C@H](O[C@H]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O