Fludarabine Phosphate (Fludara)

Name: Fludarabine Phosphate (Fludara)
SKU: A10395
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10395

Fludarabine或fludarabine phosphate（Fludara）是一种用于治疗血液系统恶性肿瘤（如白血病和淋巴瘤等血细胞癌）的化疗药物。Fludarabine通过干扰核糖核苷酸还原酶和DNA聚合酶来抑制DNA合成。它对分裂中和静息状态的细胞均有效。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥525.00	现货
50mg	¥770.00	现货
100mg	¥945.00	现货
200mg	¥1,365.00	现货
500mg	¥2,310.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10395
分子式	C10H13FN5O7P
分子量	365.2
CAS号	75607-67-9
SMILES	O[C@H]1[C@H](O)[C@H](O[C@H]1n1cnc2c1nc(F)nc2N)COP(=O)(O)O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	66 mg/mL (180.71 mM)
	Water	Warmed: 2 mg/mL (5.47 mM)
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.38 mL	136.91 mL	273.82 mL
0.5 mM	5.48 mL	27.38 mL	54.76 mL
1 mM	2.74 mL	13.69 mL	27.38 mL
5 mM	0.55 mL	2.74 mL	5.48 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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