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Flumatinib mesylate

c-Abl/c-Kit/PDGRF?? 抑制剂

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产品目录号: A13530

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Flumatinib mesylate 500mg A13530-500
¥ 1,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Flumatinib mesylate can reduce the expression of C-MYC, HIF-1 a and VEGF in U266 cell line in a time- and dose-dependent manners, so flumatinib mesylate may become a new drug for MM therapy.

Flumatinib mesylate

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Chemical Information

目录号 A13530
Mechanism of action Inhibitor
分子量 658.69
化学分子式 C30H33F3N8O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 895519-91-2
Synonyms N/A
SMILES code CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
化学名称 BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-

生物活性

Description
Flumatinib mesylate can reduce the expression of C-MYC, HIF-1 a and VEGF in U266 cell line in a time- and dose-dependent manners, so flumatinib mesylate may become a new drug for MM therapy.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.18 mL 75.91 mL 151.82mL
0.5 mM 3.04 mL 15.18 mL 30.36 mL
1 mM 1.52 mL 7.59 mL 15.18 mL
5 mM 0.3 mL 1.52 mL 3.04 mL

*The above data is based on the productmolecular weight 658.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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