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multi-kinase 抑制剂

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产品目录号: A16258


产品名 目录号 价格 数量
Flumatinib 5mg A16258-5
¥ 600.00
Flumatinib 10mg A16258-10
¥ 800.00
Flumatinib 50mg A16258-50
¥ 1,800.00



Flumatinib is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRbeta and c-Kit respectively.





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Chemical Information

目录号 A16258
Mechanism of action Inhibitor
分子量 562.59
化学分子式 C29H29F3N8O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 895519-90-1
Synonyms HHGV678, HHGV 678 , HHGV-678
SMILES code CC1=C(NC2=NC=CC(C3=CN=CC=C3)=N2)C=C(NC(C4=CC(C(F)(F)F)=C(CN5CCN(C)CC5)C=C4)=O)C=N1
化学名称 N-(6-methyl-5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)pyridin-3-yl)-4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)benzamide


Flumatinib is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRbeta and c-Kit respectively.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.77 mL 88.87 mL 177.75mL
0.5 mM 3.55 mL 17.77 mL 35.55 mL
1 mM 1.78 mL 8.89 mL 17.77 mL
5 mM 0.36 mL 1.78 mL 3.55 mL

*The above data is based on the productmolecular weight 562.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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