Flutamide
目录号: A10402
Androgen receptor 拮抗剂
Flutamide 是一种抗雄性激素药物，其活性代谢物主要通过与雄激素受体结合来发挥作用，结合常数 Ki 值为 55 nM，主要用于治疗前列腺癌。
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生物活性
| Discription | Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer. | |||||
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产品信息
| 目录号 | A10402 |
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| 分子式 | C11H11F3N2O3 |
| 分子量 | 276.21 |
| CAS号 | 13311-84-7 |
| SMILES | CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F |
| 其他名称 | SCH13521 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 51 mg/mL (184.64 mM) | |
| Water | Insoluble | ||
| Ethanol | 51 mg/mL (184.64 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.2 mL | 181.02 mL | 362.04 mL |
| 0.5 mM | 7.24 mL | 36.2 mL | 72.41 mL |
| 1 mM | 3.62 mL | 18.1 mL | 36.2 mL |
| 5 mM | 0.72 mL | 3.62 mL | 7.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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