Folinic acid calcium salt (Leucovorin)
目录号: A11110
叶酸钙盐(亦称为亚叶酸钙或左旋咪唑) 是B族维生素叶酸的活性形式,常用作抗癌治疗药物(例如甲氨蝶呤)的解毒剂,用以减少残留药物的毒性。
Discription | Folinic Acid Calcium Salt (Leucovorin) is the active form of the B complex vitamin Folate is used as an antidote to cancer treatment drugs (i.e. methotrexate) to reduce toxicity of residual drugs. | ||
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目录号 | A11110 |
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分子式 | C20H21N7O7.Ca |
分子量 | 511.51 |
CAS号 | 1492-18-8 |
SMILES | C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2] |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Insoluble | |
Water | 90 mg/mL (175.95 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.55 mL | 97.75 mL | 195.5 mL |
0.5 mM | 3.91 mL | 19.55 mL | 39.1 mL |
1 mM | 1.95 mL | 9.77 mL | 19.55 mL |
5 mM | 0.39 mL | 1.95 mL | 3.91 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2